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Volume 3
Main Index

Issue 1


Cycloaliphatic Amino Acids in Cancer Chemotherspy
Ronald B. Ross, C. I. Noll, M. V. Nadkarni, B. H. Morrison, and Howard W. Bond
pp 1 - 23; DOI:
10.1021/jm50014a001
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The Metabolism of [3-14C]Coumarin
M. Kaighen and R. T. Williams
pp 25 - 43; DOI:
10.1021/jm50014a002
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Quaternary Ammonium Compounds--I. The Antiacetylcholinesterase Action of a Series of Spiran Quaternary Ammonium Compounds
J. Thomas
pp 45 - 51; DOI:
10.1021/jm50014a003
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Structures of the Major Metabolites of Meprobamate
B. J. Ludwig, J. F. Douglas, L. S. Powell, M. Meyer, and F. M. Berger
pp 53 - 64; DOI:
10.1021/jm50014a004
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Potential Anticancer Agents--XLI. The Relationship of Chemical Structure to Antitumour Activity in Analogues of meso-1,4-Diacetoxymercuri-2,3-dimethoxybutane (NSC-2201)
Leon Goodman, Leonard O. Ross, Mary O. Greene, Joseph Greenberg, and B. R. Baker
pp 65 - 97; DOI:
10.1021/jm50014a005
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Hypoglycemic Activity in a Series of 1-Aryl-3-arylsulphonylureas
Gerald F. Holland, D. A. Jaeger, R. L. Wagner, G. D. Laubach, W. M. McLamore, and S. Y. P'an
pp 99 - 110; DOI:
10.1021/jm50014a006
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Comparative Activity of Bufadienolides
K. K. Chen and Francis G. Henderson
pp 111 - 127; DOI:
10.1021/jm50014a007
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Veratrum Alkaloids--XLIV. Structure-Activity Relationships in a Series of Synthetic Hypotensive Esters of Protoverine
S. Morris Kupchan, Ruprecht H. Hensler, and Lawrence C. Weaver
pp 129 - 155; DOI:
10.1021/jm50014a008
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The Effects of Alkyl Substitution in Drugs--III. The Spasmolytic Activity of Alkyl-Substituted Xanthene-9-Carboxylic Esters
J. Gootjes, A. B. H. Funcke, D. Mulder, H. M. Tersteege, and W. Th. Nauta
pp 157 - 165; DOI:
10.1021/jm50014a009
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Autonomic Effects of a Series of Phenylalkylamine Derivatives
M. H. Pindell, J. K. Finnegan, and J. D. Smith
pp 167 - 182; DOI:
10.1021/jm50014a010
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N-Allyl-noratropine
K. Nádor, L. György, and M. M. Doda
pp 183 - 185; DOI:
10.1021/jm50014a011
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Pyrid[2,1-c]oxazine Derivatives
F. A. Smith, L. Berger, and A. Corraz
pp 187 - 189; DOI:
10.1021/jm50014a012
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3-(p-Aminophenethyl)-5-methyl-oxazolidine-2,4-dione
Seymour L. Shapiro, Frank C. Testa, and Louis Freedman
pp 191 - 192; DOI:
10.1021/jm50014a013
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Book Review
C. Beard
pp 193 - 194; DOI:
10.1021/jm50014a014
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Issue 2


Formation of Molecular Complexes by Diketobenzodiazines and their Methylated Derivatives with Phenol and Dihydroxybenzenes in Aqueous Solutions
Takeru Higuchi, Bartley J. Sciarrone, and Amin F. Haddad
pp 195 - 213; DOI:
10.1021/jm50015a001
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Two New Synthetic Substances Active against Viruses of the Psittacosis-Lymphogranuloma-Trachoma Group
E. Weston Hurst and R. Hull
pp 215 - 229; DOI:
10.1021/jm50015a002
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New Orally Active Derivatives of α-Pyrone possessing Anti-capillary Fragility Activity--III
E. Massarani, D. Nardi, P. Mantegazza, M. Riva, and G. Cavallini
pp 231 - 240; DOI:
10.1021/jm50015a003
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Monoamine Oxidase Inhibitors--II. Some Amino and Dialkylaminobenzyl Hydrazines and their Acyl Derivatives
Thomas S. Gardner, E. Wenis, and John Lee
pp 241 - 252; DOI:
10.1021/jm50015a004
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The Synthesis and in Vitro Antibacterical Activity of Some New Nitrofuran Derivatives
David Jack
pp 253 - 263; DOI:
10.1021/jm50015a005
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A Comparative Study of the Anticancer Activity of Some S-Substituted Derivatives of 6-Mercaptopurine and their Ribonucleosides
John A. Montgomery, Thomas P. Johnston, Anne Gallagher, Carl R. Stringfellow, and Frank M. Schabel
pp 265 - 288; DOI:
10.1021/jm50015a006
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Diaryl Succinimides as Amphenone Analogues
L. I. Barsky and W. L. Bencze
pp 289 - 297; DOI:
10.1021/jm50015a007
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Chemical Models of Drug-Receptor Interaction--I. Preliminary Studies
Alexander Gero and Lida A. Shropshire
pp 299 - 307; DOI:
10.1021/jm50015a008
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Quaternary Ammonium Compounds--II. Antiacetylcholinesterase Activity and Charge Distribution in Aliphatic Quaternary Ammonium Compounds
J. Thomas
pp 309 - 321; DOI:
10.1021/jm50015a009
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Chemical Pharmacology of Catha Edulis
Gordon A. Alles, M. David Fairchild, Mark Jensen, and A. Alles
pp 323 - 352; DOI:
10.1021/jm50015a010
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Anticholinergic Compounds as Adjuncts to Atropine in Preventing Lethality by Sarin tn the Rabbit
J. H. Wills
pp 353 - 359; DOI:
10.1021/jm50015a011
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Potential Antifungal Benzhydrazides
N. T. Thu-Cuc, N. P. Buu-Hoï, and N. D. Xuong
pp 361 - 367; DOI:
10.1021/jm50015a012
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Neuromuscular Blocking Agents--VI. Linear Tetra, Penta-, and Hexa-onium Compounds
D. Edwards, J. B. Stenlake, J. J. Lewis, and Fay Stothers
pp 369 - 399; DOI:
10.1021/jm50015a013
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Basic Esters and Hydrazides Derived from Substituted Pyrrylbenzoic Acids
N. D. Xuong and N. P. Buu-Hoï
pp 401 - 404; DOI:
10.1021/jm50015a014
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Erratum ‘Comparative Activity of Bufadienolides’
Chen, and Henderson
pp 404 - 404; DOI:
10.1021/jm50015a015
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Book Reviews
Alfred Burger
pp 405 - 408; DOI:
10.1021/jm50015a017
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Issue 3


New Amorbacides--VI. The Preparation of some N,N'-Disubstituted-N,N'-bis(haloacyl)-1,4-xylylenediamines
Alexander R. Surrey and J. Richard Mayer
pp 409 - 417; DOI:
10.1021/jm50016a001
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The Preparation and Biological Activity of some N,N'-Bis(haloacyl)-polymethylenediamines
Alexander R. Surrey and J. Richard Mayer
pp 419 - 425; DOI:
10.1021/jm50016a002
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Synthesis Experiments in the Group of Hypotensive Alkaloids--XXI. Chemistry of 1,2,3,4-Tetra-hydronorharmane-1-carboxylic Acid and Derivatives
Zdeněk J. Vejdělek, Václav Trčka, and Miroslav Protiva
pp 427 - 440; DOI:
10.1021/jm50016a003
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Synthesis and Pharmacological Investigation of Derivatives of 9-Methyl-3,9-diazabicyclo-(3,3,1)-nonane
M. V. Rubtsov, M. D. Mashkovskiy, E. C. Nikitskaya, B. A. Medvedev, and V. S. Usovskaya
pp 441 - 459; DOI:
10.1021/jm50016a004
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The Synthesis of Tertiary Pyridylmethylbenzylamines
Thomas S. Gardner, E. Wenis, and John Lee
pp 461 - 470; DOI:
10.1021/jm50016a005
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N-Substituted 8-Aminomethylchromones, a new Class of Central Nervous System Stimulants
I. Setnikar, W. Murmann, M. J. Magistretti, P. Da Re, and L. Verlicchi
pp 471 - 488; DOI:
10.1021/jm50016a006
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The Pharmacology of a Series of Substituted 2-Halogenoalkylamines
J. D. P. Graham and G. W. L. James
pp 489 - 504; DOI:
10.1021/jm50016a007
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Azabenzoquinolizines with Tranquillizing Activity
Joseph G. Lombardino, J. I. Bodin, C. F. Gerber, W. M. McLamore, and G. D. Laubach
pp 505 - 517; DOI:
10.1021/jm50016a008
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S-(Alkyl- and Arylcarbamoyl)-L-cysteines
Donald L. Ross, Charles G. Skinner, and William Shive
pp 519 - 524; DOI:
10.1021/jm50016a009
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Experimental Evaluation of the Activities of Some Local Anaesthetics with Particular Reference to a New Derivative : Chloroparidocaine
B. Taccardi, G. Rapuzzi, and G. Ferrari
pp 525 - 531; DOI:
10.1021/jm50016a010
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Hydrazines, Hydrazides and Hydrazide Esters
George DeStevens, Patricia W. Strachan, Marylou Dughi, and Angela Halamandaris
pp 533 - 544; DOI:
10.1021/jm50016a011
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Local Anaesthetic Studies with Some Alkoxy-dialkylaminoalkoxyanilines
F. P. Luduena, James O. Hoppe, Donald F. Page, and R. O. Clinton
pp 545 - 553; DOI:
10.1021/jm50016a012
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Experimental Spinal Anaesthesia Produced by Members of a Homologous Series
Ernesto Gonzalez and F. P. Luduena
pp 555 - 560; DOI:
10.1021/jm50016a013
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Zur Kenntnis der Biologischen Aktivität von Chelatbildnern
H. Erlenmeyer, J. Jenni, and B. Prijs
pp 561 - 566; DOI:
10.1021/jm50016a014
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The Synthesis and Pharmacological Actions of Ortho-Substituted Phenethylhydrazines
E. L. Schumann, M. E. Greig, R. V. Heinzelman, and P. H. Seay
pp 567 - 582; DOI:
10.1021/jm50016a015
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The Anticoagulant Action of Some Derivatives of 3,3'-(Arylidene)-bis-4-hydroxycoumarin
Maria Gumińska and Marian Eckstein
pp 583 - 595; DOI:
10.1021/jm50016a016
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The Synthesis of Potential Medicinal Agents from 1-Methy-3-bromo-3-piperidyl Phenyl Ketone
Robert E. Lyle and Glenn H. Warner
pp 597 - 610; DOI:
10.1021/jm50016a017
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Monoquaternary Muscle Paralyzing Agents--II. Synthesis of N-(ω-Phthalimidoalkyl)-N-alkyl-morpholinium Iodides
Hugh B. Donahoe, Robert J. Seiwald, Sister Mary Marguerite Christine Neumann, B. V. M., and Kazuo K. Kimura
pp 611 - 614; DOI:
10.1021/jm50016a018
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On the Configuration of 14-Hydroxylated Codeine Analogues
Theodore B. Zalucky and Gilbert Hite
pp 615 - 617; DOI:
10.1021/jm50016a019
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Errata - Comparative Activity of Bufadienolides
K. K. Chen, and Francis G. Henderson
pp 618 - 618; DOI:
10.1021/jm50016a020
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Book Review
Albert H. H. Dorsey
pp 619 - 619; DOI:
10.1021/jm50016a021
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Errata - New Orally Active Derivatives of α-Pyrone Possessing Anti-capillary Fragility Activity - III
E. Massarani, D. Nardi, P. Mantegazza, M. Riva, and G. Cavallini
pp 618 - 618; DOI:
10.1021/jm50016a600
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